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The in Vivo TRPV6 Protein Starts at a Non-AUG Triplet, Decoded as Methionine, Upstream of Canonical Initiation at AUG

TRPV6 channels function as epithelial Ca(2+) entry pathways in the epididymis, prostate, and placenta. However, the identity of the endogenous TRPV6 protein relies on predicted gene coding regions and is only known to a certain level of approximation. We show that in vivo the TRPV6 protein has an ex...

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Detalhes bibliográficos
Main Authors: Fecher-Trost, Claudia, Wissenbach, Ulrich, Beck, Andreas, Schalkowsky, Pascal, Stoerger, Christof, Doerr, Janka, Dembek, Anna, Simon-Thomas, Martin, Weber, Armin, Wollenberg, Peter, Ruppert, Thomas, Middendorff, Ralf, Maurer, Hans H., Flockerzi, Veit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675598/
https://ncbi.nlm.nih.gov/pubmed/23612980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469726
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