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Abnormal calcium homeostasis and protein folding stress at the ER: A common factor in familial and infectious prion disorders
Prion-related disorders (PrDs) are caused by the accumulation of a misfolded and protease-resistant form of the cellular prion, leading to neuronal dysfunction and massive neuronal loss. In humans, PrDs have distinct etiologies including sporadic, infectious and familial forms, which present common...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187882/ https://ncbi.nlm.nih.gov/pubmed/21980554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.4.3.15019 |
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