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The Extraordinary Ability of DNA Pol λ to Stabilize Misaligned DNA

DNA polymerases have the venerable task of maintaining genome stability during DNA replication and repair. Errors, nonetheless, occur with error propensities that are polymerase specific. For example, DNA polymerase λ (pol λ) generates single-base deletions through template strand slippage within sh...

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Bibliografiske detaljer
Main Authors: Foley, Meredith C., Padow, Victoria A., Schlick, Tamar
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187873/
https://ncbi.nlm.nih.gov/pubmed/20822183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1049687
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