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Selective ablation of retinoid X receptor α in hepatocytes impairs their lifespan and regenerative capacity

Retinoid X receptors (RXRs) are involved in a number of signaling pathways as heterodimeric partners of numerous nuclear receptors. Hepatocytes express high levels of the RXRα isotype, as well as several of its putative heterodimeric partners. Germ-line disruption (knockout) of RXRα has been shown t...

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Detaylı Bibliyografya
Asıl Yazarlar: Imai, Takeshi, Jiang, Ming, Kastner, Philippe, Chambon, Pierre, Metzger, Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC31877/
https://ncbi.nlm.nih.gov/pubmed/11287642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071056098
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