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Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ER(T2)) in adipocytes

Retinoid X receptor α (RXRα) is involved in multiple signaling pathways, as a heterodimeric partner of several nuclear receptors. To investigate its function in energy homeostasis, we have selectively ablated the RXRα gene in adipocytes of 4-week-old transgenic mice by using the tamoxifen-inducible...

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Detalhes bibliográficos
Main Authors: Imai, Takeshi, Jiang, Ming, Chambon, Pierre, Metzger, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14572/
https://ncbi.nlm.nih.gov/pubmed/11134524
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