Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ER(T2)) in adipocytes
Retinoid X receptor α (RXRα) is involved in multiple signaling pathways, as a heterodimeric partner of several nuclear receptors. To investigate its function in energy homeostasis, we have selectively ablated the RXRα gene in adipocytes of 4-week-old transgenic mice by using the tamoxifen-inducible...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011528898 |
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