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Selective ablation of retinoid X receptor α in hepatocytes impairs their lifespan and regenerative capacity
Retinoid X receptors (RXRs) are involved in a number of signaling pathways as heterodimeric partners of numerous nuclear receptors. Hepatocytes express high levels of the RXRα isotype, as well as several of its putative heterodimeric partners. Germ-line disruption (knockout) of RXRα has been shown t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31877/ https://ncbi.nlm.nih.gov/pubmed/11287642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071056098 |
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