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Cooperative Role of Caveolin-1 and C-Terminal Src Kinase Binding Protein in C-Terminal Src Kinase-Mediated Negative Regulation of c-Src

In the present study, we assessed the cooperative roles of C-terminal Src kinase (Csk) binding protein (Cbp) and Caveolin-1 (Cav-1) in the mechanism of Src family tyrosine kinase (SFK) inhibition by Csk. SFKs are inactivated by phosphorylation of their C-terminal tyrosine by Csk. Whereas SFKs are me...

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Autors principals: Place, Aaron T., Chen, Zhenlong, Bakhshi, Farnaz R., Liu, Guoquan, O'Bryan, John P., Minshall, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187524/
https://ncbi.nlm.nih.gov/pubmed/21778303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073957
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