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Early emergence of negative regulation of the tyrosine kinase Src by the C-terminal Src kinase

Stringent regulation of tyrosine kinase activity is essential for normal cellular function. In humans, the tyrosine kinase Src is inhibited via phosphorylation of its C-terminal tail by another kinase, C-terminal Src kinase (Csk). Although Src and Csk orthologs are present across holozoan organisms,...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Taskinen, Barbara, Ferrada, Evandro, Fowler, Douglas M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682962/
https://ncbi.nlm.nih.gov/pubmed/28939764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811174
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