A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

Detachment of epithelial cells from matrix or attachment to an inappropriate matrix engages an apoptotic response known as anoikis, which prevents metastasis. Cellular sensitivity to anoikis is compromised during the oncogenic epithelial-to-mesenchymal transition (EMT), through unknown mechanisms. W...

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Bibliographic Details
Main Authors: Kumar, Sanjeev, Park, Sun Hee, Cieply, Benjamin, Schupp, Jane, Killiam, Elizabeth, Zhang, Fan, Rimm, David L., Frisch, Steven M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187352/
https://ncbi.nlm.nih.gov/pubmed/21746881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01342-10
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