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A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

Detachment of epithelial cells from matrix or attachment to an inappropriate matrix engages an apoptotic response known as anoikis, which prevents metastasis. Cellular sensitivity to anoikis is compromised during the oncogenic epithelial-to-mesenchymal transition (EMT), through unknown mechanisms. W...

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Главные авторы: Kumar, Sanjeev, Park, Sun Hee, Cieply, Benjamin, Schupp, Jane, Killiam, Elizabeth, Zhang, Fan, Rimm, David L., Frisch, Steven M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187352/
https://ncbi.nlm.nih.gov/pubmed/21746881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01342-10
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