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A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

Detachment of epithelial cells from matrix or attachment to an inappropriate matrix engages an apoptotic response known as anoikis, which prevents metastasis. Cellular sensitivity to anoikis is compromised during the oncogenic epithelial-to-mesenchymal transition (EMT), through unknown mechanisms. W...

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Autori principali: Kumar, Sanjeev, Park, Sun Hee, Cieply, Benjamin, Schupp, Jane, Killiam, Elizabeth, Zhang, Fan, Rimm, David L., Frisch, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187352/
https://ncbi.nlm.nih.gov/pubmed/21746881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01342-10
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