Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelial-mesenchymal Transition: Effects on Anoikis

Resistance to anoikis is a pre-requisite for tumor metastasis. The epithelial-to-mesenchymal transition (EMT) allows tumor cells to evade anoikis. The wound healing regulatory transcription factor Grainyhead-like 2 (GRHL2) suppresses/reverses EMT, accompanied by suppression of the cancer stem cell (...

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Bibliographic Details
Published in:Mol Cancer Res
Main Authors: Farris, Joshua C., Pifer, Phillip M., Zheng, Liang, Gottlieb, Eyal, Denvir, James, Frisch, Steven M.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912396/
https://ncbi.nlm.nih.gov/pubmed/27084311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0050
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