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Competitive Regulation of Nucleolin Expression by HuR and miR-494

The RNA-binding protein (RBP) nucleolin promotes the expression of several proliferative proteins. Nucleolin levels are high in cancer cells, but the mechanisms that control nucleolin expression are unknown. Here, we show that nucleolin abundance is controlled posttranscriptionally via factors that...

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Bibliografiske detaljer
Main Authors: Tominaga, Kumiko, Srikantan, Subramanya, Lee, Eun Kyung, Subaran, Sarah S., Martindale, Jennifer L., Abdelmohsen, Kotb, Gorospe, Myriam
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187287/
https://ncbi.nlm.nih.gov/pubmed/21859890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05955-11
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