Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity

It has been shown that inhibition of de novo sphingolipid synthesis increases insulin sensitivity. For further exploration of the mechanism involved, we utilized two models: heterozygous serine palmitoyltransferase (SPT) subunit 2 (Sptlc2) gene knockout mice and sphingomyelin synthase 2 (Sms2) gene...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Li, Zhiqiang, Zhang, Hongqi, Liu, Jing, Liang, Chien-Ping, Li, Yan, Li, Yue, Teitelman, Gladys, Beyer, Thomas, Bui, Hai H., Peake, David A., Zhang, Youyan, Sanders, Phillip E., Kuo, Ming-Shang, Park, Tae-Sik, Cao, Guoqing, Jiang, Xian-Cheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2011
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187286/
https://ncbi.nlm.nih.gov/pubmed/21844222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05893-11
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