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Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated PPARγ2 suppression
OBJECTIVE: Sphingomyelin Sphingolipid de novo biosynthesis is related with nonalcoholic fatty liver disease (NAFLD) or hepatic steatosis. However, the mechanism is still unclear. Sphingomyelin synthase (SMS), utilizing ceramide as one of the substrates to produce sphingomyelin, sits at the crossroad...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784343/ https://ncbi.nlm.nih.gov/pubmed/23640498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301498 |
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