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Sphingomyelin synthase overexpression increases cholesterol accumulation and decreases cholesterol secretion in liver cells

BACKGROUND: Studies have shown that plasma high density lipoprotein cholesterol levels are negatively correlated with the development of atherosclerosis, whereas epidemiological studies have also shown that plasma sphingomyelin level is an independent risk factor for atherosclerosis. METHODS: To eva...

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Detalhes bibliográficos
Main Authors: Yan, Nianlong, Ding, Tingbo, Dong, Jibin, Li, Yue, Wu, Manping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070670/
https://ncbi.nlm.nih.gov/pubmed/21418611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-46
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