Pharmacologic Inhibition of Sphingomyelin Synthase (SMS) Activity Reduces Apolipoprotein-B Secretion from Hepatocytes and Attenuates Endotoxin-Mediated Macrophage Inflammation

Sphingomyelin synthase (SMS) plays an important role in plasma atherogenic lipoprotein metabolism, inflammation, and the development of atherosclerosis. To understand whether the impaired apoB secretion and inflammation response is a direct result from lack of SMS activity, in this study, we prepare...

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Detaylı Bibliyografya
Asıl Yazarlar: Lou, Bin, Dong, Jibin, Li, Yali, Ding, Tingbo, Bi, Tingting, Li, Yue, Deng, Xiaodong, Ye, Deyong, Jiang, Xian-Cheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102531/
https://ncbi.nlm.nih.gov/pubmed/25032960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102641
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