Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm

Granzyme B (GZMB) is a proapoptotic serine protease that is released by cytotoxic lymphocytes. However, GZMB can also be produced by other cell types and is capable of cleaving extracellular matrix (ECM) proteins. GZMB contributes to abdominal aortic aneurysm (AAA) through an extracellular, perforin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ang, L S, Boivin, W A, Williams, S J, Zhao, H, Abraham, T, Carmine-Simmen, K, McManus, B M, Bleackley, R C, Granville, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186906/
https://ncbi.nlm.nih.gov/pubmed/21900960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.88
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados