Krüppel-like Factor 5 is Important for Maintenance of Crypt Architecture and Barrier Function in Mouse Intestine

BACKGROUND & AIMS: Krüppel-like factor 5 (KLF5) is transcription factor that is expressed by dividing epithelial cells of the intestinal epithelium. KLF5 promotes proliferation in vitro and in vivo and is induced by mitogens and various stress stimuli. To study the role of KLF5 in intestinal epi...

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Hauptverfasser: McConnell, Beth B., Kim, Samuel S., Yu, Ke, Ghaleb, Amr M., Takeda, Norifumi, Manabe, Ichiro, Nusrat, Asma, Nagai, Ryozo, Yang, Vincent W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186863/
https://ncbi.nlm.nih.gov/pubmed/21763241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.086
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