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Role of Krüppel-like factor 5 in the maintenance of the stem cell niche in the intestinal crypt

The intestinal epithelium is a tissue that undergoes continuous self-renewal initiated at the bottom of the crypts, which harbor the intestinal stem cell (ISC) pool. The ISC pool is sub-divided into crypt base columnar (CBC) cells at the crypt bottom and label retention cells (LRC) at position +4 fr...

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Publicado en:Stem Cell Transl Investig
Autores principales: Kuruvilla, Jes G., Ghaleb, Amr M., Bialkowska, Agnieszka B., Nandan, Mandayam O., Yang, Vincent W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474380/
https://ncbi.nlm.nih.gov/pubmed/26097895
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