Llwytho...

Deletion of Syk kinase in neutrophils prevents immune complex arthritis

The K/BxN serum transfer model of arthritis is critically dependent on FcγR signaling events mediated by Syk kinase. However, the specific cell types in which this signaling is required are not known. We report that deletion of Syk kinase in neutrophils, achieved using syk(f/f) MRP8-cre(+) mice, blo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Elliott, Emily R., Van Ziffle, Jessica A., Scapini, Patrizia, Sullivan, Brandon M., Locksley, Richard M., Lowell, Clifford A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186826/
https://ncbi.nlm.nih.gov/pubmed/21918195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100341
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