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Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection

Leukocyte-specific CD18 integrins are critical in mediating cell recruitment and activation during host defense responses to bacterial infection. The signaling pathways downstream of CD18 integrins are dependent on the spleen tyrosine kinase, Syk. To investigate the role integrin signaling plays in...

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Detalhes bibliográficos
Main Authors: Van Ziffle, Jessica A., Lowell, Clifford A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786293/
https://ncbi.nlm.nih.gov/pubmed/19797524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-220806
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