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Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
Leukocyte-specific CD18 integrins are critical in mediating cell recruitment and activation during host defense responses to bacterial infection. The signaling pathways downstream of CD18 integrins are dependent on the spleen tyrosine kinase, Syk. To investigate the role integrin signaling plays in...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786293/ https://ncbi.nlm.nih.gov/pubmed/19797524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-220806 |
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