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Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection

The appropriate regulation of neutrophil activation is critical for maintaining host defense and limiting inflammation. Neutrophils (PMNs) express a number of cytoplasmic tyrosine kinases that regulate signaling pathways leading to activation. One of the most highly expressed, but least studied, kin...

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Detalhes bibliográficos
Main Authors: Kamen, Lynn A., Schlessinger, Joseph, Lowell, Clifford A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248398/
https://ncbi.nlm.nih.gov/pubmed/21187437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002093
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