Neutrophils Are Required During Immunization With the Pneumococcal Conjugate Vaccine for Protective Antibody Responses and Host Defense Against Infection

Neutrophils can shape adaptive immunity; however, their role in vaccine-induced protection against infections in vivo remains unclear. Here, we tested their role in the clinically relevant polysaccharide conjugate vaccine against Streptococcus pneumoniae (pneumococcus). We antibody depleted neutroph...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Tchalla, Essi Y I, Bhalla, Manmeet, Wohlfert, Elizabeth A, Bou Ghanem, Elsa N
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488200/
https://ncbi.nlm.nih.gov/pubmed/32391562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa242
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