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Deletion of Syk kinase in neutrophils prevents immune complex arthritis
The K/BxN serum transfer model of arthritis is critically dependent on FcγR signaling events mediated by Syk kinase. However, the specific cell types in which this signaling is required are not known. We report that deletion of Syk kinase in neutrophils, achieved using syk(f/f) MRP8-cre(+) mice, blo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186826/ https://ncbi.nlm.nih.gov/pubmed/21918195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100341 |
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