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Functional Importance of Covalent Homodimer of Reelin Protein Linked via Its Central Region
Reelin is a 3461-residue secreted glycoprotein that plays a critical role in brain development through its action on target neurons. Although it is known that functional reelin protein exists as multimer formed by interchain disulfide bond(s) as well as through non-covalent interactions, the chemica...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186359/ https://ncbi.nlm.nih.gov/pubmed/21844191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.242719 |
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