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Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders
The secreted glycoprotein Reelin is believed to play critical roles in the pathogenesis of several neuropsychiatric disorders. The highly basic C-terminal region (CTR) of Reelin is necessary for efficient activation of its downstream signaling, and the brain structure of knock-in mice that lack the...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4921851/ https://ncbi.nlm.nih.gov/pubmed/27346785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28636 |
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