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Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography

The large extracellular glycoprotein reelin directs neuronal migration during brain development and plays a fundamental role in layer formation. It is composed of eight tandem repeats of an ∼380-residue unit, termed the reelin repeat, which has a central epidermal growth factor (EGF) module flanked...

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Hlavní autoři: Nogi, Terukazu, Yasui, Norihisa, Hattori, Mitsuharu, Iwasaki, Kenji, Takagi, Junichi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538547/
https://ncbi.nlm.nih.gov/pubmed/16858396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601240
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