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Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography
The large extracellular glycoprotein reelin directs neuronal migration during brain development and plays a fundamental role in layer formation. It is composed of eight tandem repeats of an ∼380-residue unit, termed the reelin repeat, which has a central epidermal growth factor (EGF) module flanked...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1538547/ https://ncbi.nlm.nih.gov/pubmed/16858396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601240 |
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