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Histones induce rapid and profound thrombocytopenia in mice

Histones are released from dying cells and contribute to antimicrobial defense during infection. However, extracellular histones are a double-edged sword because they also damage host tissue and may cause death. We studied the interactions of histones with platelets. Histones bound to platelets, ind...

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Detalhes bibliográficos
Main Authors: Fuchs, Tobias A., Bhandari, Ashish A., Wagner, Denisa D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186342/
https://ncbi.nlm.nih.gov/pubmed/21700775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-332676
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