Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor β growth inhibition in p16(INK4A)(−) human mammary epithelial cells

Failures to arrest growth in response to senescence or transforming growth factor β (TGF-β) are key derangements associated with carcinoma progression. We report that activation of telomerase activity may overcome both inhibitory pathways. Ectopic expression of the human telomerase catalytic subunit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Stampfer, Martha R., Garbe, James, Levine, Gerri, Lichtsteiner, Serge, Vasserot, Alain P., Yaswen, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC31863/
https://ncbi.nlm.nih.gov/pubmed/11287649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071483998
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge