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Krüppel-like Factor 2 Represses Transcription of the Telomerase Catalytic Subunit Human Telomerase Reverse Transcriptase (hTERT) in Human T Cells
In normal human T cells, telomerase activity is strictly regulated. T cells are thought to express telomerase to avoid replicative senescence, unlike most normal somatic cells with definite replicative lifespan. T cells in blood and tissues are usually in a state of quiescence without expression of...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423666/ https://ncbi.nlm.nih.gov/pubmed/25694435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610386 |
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