Blockade of Endocannabinoid Hydrolytic Enzymes Attenuates Precipitated Opioid Withdrawal Symptoms in Mice

Δ(9)-Tetrahydrocannbinol (THC), the primary active constituent of Cannabis sativa, has long been known to reduce opioid withdrawal symptoms. Although THC produces most of its pharmacological actions through the activation of CB(1) and CB(2) cannabinoid receptors, the role these receptors play in red...

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Hlavní autoři: Ramesh, Divya, Ross, Gracious R., Schlosburg, Joel E., Owens, Robert A., Abdullah, Rehab A., Kinsey, Steven G., Long, Jonathan Z., Nomura, Daniel K., Sim-Selley, Laura J., Cravatt, Benjamin F., Akbarali, Hamid I., Lichtman, Aron H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
Behavioral Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186294/
https://ncbi.nlm.nih.gov/pubmed/21719468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.181370
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