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2',3'-Dideoxy-3' aminonucleoside 5'-triphosphates are the terminators of DNA synthesis catalyzed by DNA polymerases.

It is shown that 2',3'-dideoxy-3'-aminonucleoside 5'-triphosphates with adenine, guanine, cytosine and thymine bases are effective inhibitors of DNA polymerase I, calf thymus DNA polymerase alpha and rat liver DNA polymerase beta. The effect of the above-mentioned compounds is ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chidgeavadze, Z G, Beabealashvilli, R S, Atrazhev, A M, Kukhanova, M K, Azhayev, A V, Krayevsky, A A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC318607/
https://ncbi.nlm.nih.gov/pubmed/6322115
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