2',3'-Dideoxy-3' aminonucleoside 5'-triphosphates are the terminators of DNA synthesis catalyzed by DNA polymerases.

It is shown that 2',3'-dideoxy-3'-aminonucleoside 5'-triphosphates with adenine, guanine, cytosine and thymine bases are effective inhibitors of DNA polymerase I, calf thymus DNA polymerase alpha and rat liver DNA polymerase beta. The effect of the above-mentioned compounds is ma...

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Bibliographic Details
Main Authors: Chidgeavadze, Z G, Beabealashvilli, R S, Atrazhev, A M, Kukhanova, M K, Azhayev, A V, Krayevsky, A A
Format: Artigo
Language:Inglês
Published: 1984
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC318607/
https://ncbi.nlm.nih.gov/pubmed/6322115
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