Computational Modeling of Interacting VEGF and Soluble VEGF Receptor Concentration Gradients

Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To better delineate the role of sFlt-1 in VEGF signaling, we have developed an experimentally based computational model. T...

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Detalhes bibliográficos
Main Authors: Hashambhoy, Yasmin L., Chappell, John C., Peirce, Shayn M., Bautch, Victoria L., Mac Gabhann, Feilim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185289/
https://ncbi.nlm.nih.gov/pubmed/22007175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2011.00062
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