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Agent-based Computational Model of Retinal Angiogenesis Simulates Microvascular Network Morphology as a Function of Pericyte Coverage

OBJECTIVE: Define a role for perivascular cells during developmental retinal angiogenesis in the context of endothelial cell Notch1-DLL4 signaling at the multicellular network level. METHODS: The retinal vasculature is highly sensitive to growth factor mediated intercellular signaling. Although endo...

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Detalhes bibliográficos
Publicado no:Microcirculation
Main Authors: Walpole, Joseph, Mac Gabhann, Feilim, Peirce, Shayn M, Chappell, John C
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673505/
https://ncbi.nlm.nih.gov/pubmed/28791758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12393
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