Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport

Vascular endothelial growth factor (VEGF) signal transduction through the cell surface receptors VEGFR1 and VEGFR2 regulates angiogenesis—the growth of new capillaries from preexistent microvasculature. Soluble VEGF receptor-1 (sVEGFR1), a nonsignaling truncated variant of VEGFR1, has been postulate...

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Detalhes bibliográficos
Main Authors: Wu, Florence T. H., Stefanini, Marianne O., Mac Gabhann, Feilim, Kontos, Christopher D., Annex, Brian H., Popel, Aleksander S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Call for Papers: Computational Modeling of Physiological Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696151/
https://ncbi.nlm.nih.gov/pubmed/19351908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00031.2009
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