Binding of Activating Transcription Factor 6 to the A5/Core of the Rat Insulin II Gene Promoter does not Mediate its Transcriptional Repression

Pancreatic β-cells have a well-developed endoplasmic reticulum (ER) due to their highly specialized secretory function to produce insulin in response to glucose and nutrients. It has been previously reported that overexpression of activating transcription factor 6 (ATF6) reduces insulin gene express...

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Bibliographic Details
Main Authors: Amyot, Julie, Benterki, Isma, Fontés, Ghislaine, Hagman, Derek K., Ferdaoussi, Mourad, Teodoro, Tracy, Volchuk, Allen, Joly, Érik, Poitout, Vincent
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185209/
https://ncbi.nlm.nih.gov/pubmed/21821716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-11-0016
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