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Binding of Activating Transcription Factor 6 to the A5/Core of the Rat Insulin II Gene Promoter does not Mediate its Transcriptional Repression
Pancreatic β-cells have a well-developed endoplasmic reticulum (ER) due to their highly specialized secretory function to produce insulin in response to glucose and nutrients. It has been previously reported that overexpression of activating transcription factor 6 (ATF6) reduces insulin gene express...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185209/ https://ncbi.nlm.nih.gov/pubmed/21821716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-11-0016 |
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