Characterization of the Human SLC30A8 Promoter and Intronic Enhancer

Genome-wide association (GWA) studies have shown that a polymorphic variant in SLC30A8, which encodes zinc transporter-8 (ZnT-8), is associated with altered susceptibility to type 2 diabetes (T2D). This association is consistent with the observation that glucose-stimulated insulin secretion is decre...

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Main Authors: Pound, Lynley D., Sarkar, Suparna A., Cauchi, Stéphane, Wang, Yingda, Oeser, James K., Lee, Catherine E., Froguel, Philippe, Hutton, John C., O'Brien1, Richard M.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185167/
https://ncbi.nlm.nih.gov/pubmed/21798992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-11-0055
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