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Modulation of the Processive Abasic Site Lyase Activity of a Pyrimidine Dimer Glycosylase
The repair of cis-syn cyclobutane pyrimidine dimers (CPDs) can be initiated via the base excision repair (BER) pathway, utilizing pyrimidine dimer-specific DNA glycosylase/lyase enzymes (pdgs). However, prior to incision at lesion sites, these enzymes bind to non-damaged DNAs through charge-charge i...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2011
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185154/ https://ncbi.nlm.nih.gov/pubmed/21889915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.07.015 |
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