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Uncoupling of nucleotide flipping and DNA bending by the T4-pyrimidine dimer DNA glycosylase

Bacteriophage T4 pyrimidine dimer glycosylase (T4-Pdg) is a base excision repair protein that incises DNA at cyclobutane pyrimidine dimers that are formed as a consequence of exposure to ultraviolet light. Cocrystallization of T4-Pdg with substrate DNA has shown that the adenosine opposite the 5′ th...

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Sonraí Bibleagrafaíochta
Main Authors: Walker, Randall K., McCullough, Amanda K., Lloyd, R. Stephen
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673921/
https://ncbi.nlm.nih.gov/pubmed/17115714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060802s
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