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Uncoupling of nucleotide flipping and DNA bending by the T4-pyrimidine dimer DNA glycosylase
Bacteriophage T4 pyrimidine dimer glycosylase (T4-Pdg) is a base excision repair protein that incises DNA at cyclobutane pyrimidine dimers that are formed as a consequence of exposure to ultraviolet light. Cocrystallization of T4-Pdg with substrate DNA has shown that the adenosine opposite the 5′ th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673921/ https://ncbi.nlm.nih.gov/pubmed/17115714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060802s |
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