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N-terminus of the rat adenine glycosylase MYH affects excision rates and processing of MYH-generated abasic sites

Repair of most modified and mispaired bases in the genome is initiated by DNA glycosylases, which bind to their respective targets and cleave the N-glycosyl bond to initiate base excision repair (BER). The mammalian homolog of the Escherichia coli MutY DNA glycosylase (MYH) cleaves adenine residues...

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Detalles Bibliográficos
Main Authors: Ma, Huaxian, Lee, Heung M., Englander, Ella W.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC514379/
https://ncbi.nlm.nih.gov/pubmed/15310837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh758
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