Modulation of the Processive Abasic Site Lyase Activity of a Pyrimidine Dimer Glycosylase

The repair of cis-syn cyclobutane pyrimidine dimers (CPDs) can be initiated via the base excision repair (BER) pathway, utilizing pyrimidine dimer-specific DNA glycosylase/lyase enzymes (pdgs). However, prior to incision at lesion sites, these enzymes bind to non-damaged DNAs through charge-charge i...

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Main Authors: Ryabinina, Olga, Minko, Irina G., Lasarev, Michael, McCullough, Amanda K., Lloyd, R. Stephen
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185154/
https://ncbi.nlm.nih.gov/pubmed/21889915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.07.015
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