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Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma

Although the molecular changes that characterize gliomas have been studied, the pathogenesis of tumor development remains unclear. p21 contributes to gliomagenesis by stabilizing cyclin D1-cdk4 kinase complexes, suggesting that cyclin D1 and cdk4 may also be required for glial tumor development. In...

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Bibliografski detalji
Glavni autori: Ciznadija, Daniel, Liu, Yuhui, Pyonteck, Stephanie M., Holland, Eric C., Koff, Andrew
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185142/
https://ncbi.nlm.nih.gov/pubmed/21844184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1031
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