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THE STRUCTURE OF NS-398 BOUND TO CYCLOOXYGENASE-2
The cyclooxygenases (COX-1 and COX-2) are membrane-associated, heme-containing homodimers that generate prostaglandin H(2) from arachidonic acid (AA) in the committed step of prostaglandin biogenesis and are the targets for nonsteroidal anti-inflammatory drugs (NSAIDs). N-(2-cyclohexyloxy-4-nitrophe...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185125/ https://ncbi.nlm.nih.gov/pubmed/21843643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.07.019 |
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