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Site-specific cleavage of supercoiled DNA by ascorbate/Cu(II).
We have investigated ascorbate/Cu(II) cleavage of double-stranded DNA in the presence and absence of DNA negative torsion. We found that ascorbate/Cu(II) cleavage shows a site-specificity that is dependent on negative torsion and is influenced by the nature of the salt, ionic strength, and pH. This...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1989
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318422/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2780314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.17.6915 |
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