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Stoichiometric incorporation of base substitutions at specific sites in supercoiled DNA and supercoiled recombination intermediates

Supercoiled DNA is the relevant substrate for a large number of DNA transactions and has additionally been found to be a favorable form for delivering DNA and protein-DNA complexes to cells. We report here a facile method for stoichiometrically incorporating several different modifications at multip...

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Detalhes bibliográficos
Principais autores: Matovina, Mihaela, Seah, Nicole, Hamilton, Theron, Warren, David, Landy, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952878/
https://ncbi.nlm.nih.gov/pubmed/20693535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq674
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